Our Projects

Directed by Lison Lachize Léanne (PhD student).

Study of the involvement of TNF members in cIgAN, in particular the interactions between APRIL, BAFF and the complement system.

Produced by Amandine Badie (Postdoctoral Researcher) in collaboration with Dr Alexandra Dubrac and Dr Gilles Hickson.

Study of the mechanisms by which soluble CD89 induces renal inflammation and activates the mTOR pathway, cytokines and complement via the TfR1 receptor.

Directed by Srishti Sahu (PhD student).

In vitro (cell models) and in vivo (patient cohort) studies to better understand the involvement of complement in cIgAN.

Directed by Diane Leenhardt (M.Sc.) and Dr Helene Mathieu.

In vitro study on podocytes to evaluate complement activation and C5b9 deposition after stimulation with serum from affected patients. Analysis of the complement pathway in a cohort of patients with nephrotic syndrome.